Trauma Center: Second Opinion
Released in November 2006, on the launch day of the Wii, sadists rejoiced as this remake of the DS game Trauma Center: Under the Knife let gamers continue
inflicting grotesque bodily harm upon their victims treating patients, except with a Wiimote instead of a DS stylus. A new character, Nozomi Weaver, and new missions were added for the Wii release. The game again has the mysterious disease GUILT (Gangliated Utrophin Immuno Latency Toxin) threatening mankind, and it's up to Dr. Derek Stiles to prevent GUILT from spreading.